To print: Select File and then Print from your browser's menu --------------------------------------------------------------------------------------- Title: DG DISPATCH - AUA: Topical alprostadil produces significant clitoral hemodynamic changes URL: http://www.pslgroup.com/dg/1CF5A2.htm Doctor's Guide May 2, 2000
By Emma Patten Special to DG News ATLANTA, GA -- May 2, 2000 -- The vasoactive drug alprostadil can be used to mimic the hemodynamic effects of self-stimulation, researchers report. Consequently, alprostadil may be a useful alternative to self-stimulation in the preparation of patients for ultrasound of clitoral arteries. Edgardo F. Becher, MD, and colleagues from the University of Buenos Aires, in Buenos Aires, Argentina, reported their results Monday (May 1) at the American Urological Association's 95th Annual Meeting, in Atlanta, GA. The group used color duplex ultrasound to evaluate 18 women, aged 18 to 61 years (average age 42.5 years), before and after administrating 1g of alprostadil cream 0.2%. The group then evaluated clitoral arteries sagitally using a 7.5 MHz linear probe. "If sexual stimulation is not available or acceptable, either from the physician or patient's point of view, then this cream could be used to create the vasodilatory effect that is necessary to evaluate an artery," explained Dr. Becher. The parameters measured included peak systolic velocity, end diastolic velocity, and resistance index. All women experienced labial and clitoral engorgement, 13 women (72 percent) reported a pleasant sensation of warmth in the genital area, and 11 percent reported mild burning. No systemic effects were found. "The findings are similar to those reported after sexual stimulation, showing that topical vasoactive drugs may help in the evaluation of women suffering from sexual dysfunction," the researchers note. "Further research will dictate its role in clinical applications." --------------------------------------------------------------------------------------------- Copyright © 1999 P\S\L Consulting Group Inc. All rights reserved. Republication or redistribution of P\S\L content is expressly prohibited without the prior written consent of P\S\L. P\S\L shall not be liable for any errors, omissions or delays in this content or any other content on its sites, newsletters or other publications, nor for any decisions or actions taken in reliance on such content. --------------------------------------------------------------------------------------------- This news story was printed from *Doctor's Guide to the Internet* located at http://www.docguide.com --------------------------------------------------------------------------------------- Return to News Story Page This site is maintained by webmaster@pslgroup.com Please contact us with any comments, problems or bugs. All contents Copyright (c) 1998 P\S\L Consulting Group Inc. All rights reserved.