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Title: Newer CT Machines Effective in Detecting Coronary Artery Stenosis
URL: http://www.pslgroup.com/dg/229F52.htm
Doctor's Guide
August 26, 2008


TORRANCE, California -- August 26, 2008 -- The latest cardiac imaging technology is 99% as effective in ruling out obstructive coronary artery stenosis compared with the more expensive and invasive coronary angiography traditionally used by physicians, according to a study published early in the Journal of the American College of Cardiology.

"The research found this noninvasive method of cardiac imaging will effectively detect stenosis -- a constriction or narrowing -- of the coronary arteries that can lead to heart attacks and may require surgery to repair," said lead author Matthew J. Budoff, MD, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed), Los Angeles, California.

"This is good news for patients who, in the past, might have been forced to undergo a more expensive and invasive procedure to determine if they suffered from blockages in the arteries leading to their hearts."

The multicentre study included 230 participants with chest pain but no known coronary artery disease. All participants were examined using some of the newer cardiac CT technology, including electrocardiographically gated 64-multidetector row coronary computed tomographic angiography (CCTA).

Each participant also underwent the "gold standard," more expensive, and invasive coronary angiography.

The researchers found that CCTA provided high diagnostic accuracy for detection of obstructive coronary stenosis at the thresholds of a 50% narrowing and at 70% stenosis. It also found that CCTA was accurate 99% of the time in ruling out coronary artery stenosis.

SOURCE: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)

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