To print: Select File and then Print from your browser's menu --------------------------------------------------------------------------------------- Title: DG DISPATCH - APA: Paroxetine Effective Against Hot Flushes in Survivors of Breast Cancer URL: http://www.pslgroup.com/dg/1D291E.htm Doctor's Guide May 19, 2000
By Lara Pullen Special to DG News
CHICAGO, IL -- May 19, 2000 -- A recent paroxetine study demonstrated substantial reduction in hot flushes and improvement in menopausal symptoms among breast cancer survivors.
At the 2000 Annual Meeting of the American Psychiatric Association, in Chicago, IL, Kate Beebe, MD, of SmithKline Beecham Pharmaceuticals, presented the results of a five-week, open-label trial designed to evaluate changes in mood, anxiety, sleep, sexual function, and overall quality of life in perimenopausal with paroxetine.
The study included 27 women over the age of 18 who had a history of breast cancer. The patients had a minimum of 14 hot flushes per week over at least one month. Patients undergoing cytotoxic chemotherapy, hormonal therapy other than tamoxifen, antidepressants, or other therapies for hot flushes (except for Vitamin E) were excluded from the study.
The study found a 67 percent mean reduction in hot flushes. Of the 27 women, 67 percent responded with a greater than 50 percent reduction in the daily number of hot flushes (the typical placebo response is 27 percent). Patients treated with paroxetine experienced a significant improvement in overall quality of life and paroxetine was generally well tolerated.
More than 80 percent of enrolled women chose to continue treatment at study conclusion. Results from a large double-blind placebo-controlled trial of paroxetine are expected this year. Related links: Paroxetine. --------------------------------------------------------------------------------------------- Copyright © 1999 P\S\L Consulting Group Inc. All rights reserved. Republication or redistribution of P\S\L content is expressly prohibited without the prior written consent of P\S\L. P\S\L shall not be liable for any errors, omissions or delays in this content or any other content on its sites, newsletters or other publications, nor for any decisions or actions taken in reliance on such content. --------------------------------------------------------------------------------------------- This news story was printed from *Doctor's Guide to the Internet* located at http://www.docguide.com --------------------------------------------------------------------------------------- Return to News Story Page This site is maintained by webmaster@pslgroup.com Please contact us with any comments, problems or bugs. All contents Copyright (c) 1998 P\S\L Consulting Group Inc. All rights reserved.