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Title: DG Dispatch - AAN: Epileptic Drug Used To Treat MS Symptom
URL: http://www.pslgroup.com/dg/F80F2.htm
Doctor's Guide
April 20, 1999


By Cameron Johnston
Special to DG News

TORONTO, ON -- April 20, 1999 -- Low-dose Neurontin (gabapentin) may be useful in treating painful night-time spasms in adults with multiple sclerosis (MS), according to a study presented at the American Academy of Neurology meeting being held in Toronto from April 17-24.

Parke-Davis' Neurontin is currently used to treat partial generalised epileptic seizures in children.

People with epilepsy may take up to 1,800 mg/day of the drug, while patients enrolled in the MS study were given no more than 600 mg/day. They were then tested after two weeks and eight weeks of treatment. Neurologist Gianluigi Marcardi, from Genoa, Italy, reported that 20 out of 24 patients who used gabapentin reported that their spasms either cleared up completely or were significantly reduced over the course of the study.

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