To print: Select File and then Print from your browser's menu --------------------------------------------------------------------------------------- Title: DG DISPATCH - AACAP: Bupropion SR Effective In Treating Adult AD/HD URL: http://www.pslgroup.com/dg/13E7A2.htm Doctor's Guide October 26, 1999
By Lara Pullen Special to DG News
CHICAGO, IL -- October 26, 1999 -- Despite the increased recognition of adult attention deficit/hyperactivity disorder (AD/HD), there are very few placebo-controlled clinical trials addressing its pharmacotherapy. A new study indicates that bupropion SR (sustained release) results in clinically and statistically significant improvement of AD/HD in adults.
At the 46th annual meeting of the American Academy of Child and Adolescent Psychiatry, Dr. Timothy E. Wilens, of Massachusetts General Hospital, in Boston, presented the results of a randomized, double-blind, placebo-controlled trial. This trial follows an open report that suggested the usefulness of bupropion SR in adults with AD/HD.
The study comprised 40 adults (18 women/22 men) with a mean age of 38 years. Bupropion SR was initiated at 100 mg/day and titrated by 100 mg/day at weekly intervals to a target dose of 400 mg/day (200 mg twice daily).
The results show bupropion SR treatment was associated with a significant reduction in AD/HD symptoms which exceeded placebo at the end of the six-week treatment period. Seventy-six percent of subjects on bupropion SR were judged under blind conditions to have a positive response to treatment. The mean dose of bupropion SR was 362 mg/day. The bulk of improvement in AD/HD symptoms occurred after week four, suggesting either a titration effect or delayed onset of action.
Related Link: bupropion SR (sustained release). --------------------------------------------------------------------------------------------- Copyright © 1999 P\S\L Consulting Group Inc. All rights reserved. Republication or redistribution of P\S\L content is expressly prohibited without the prior written consent of P\S\L. P\S\L shall not be liable for any errors, omissions or delays in this content or any other content on its sites, newsletters or other publications, nor for any decisions or actions taken in reliance on such content. --------------------------------------------------------------------------------------------- This news story was printed from *Doctor's Guide to the Internet* located at http://www.docguide.com --------------------------------------------------------------------------------------- Return to News Story Page This site is maintained by webmaster@pslgroup.com Please contact us with any comments, problems or bugs. All contents Copyright (c) 1998 P\S\L Consulting Group Inc. All rights reserved.