To print: Select File and then Print from your browser's menu
---------------------------------------------------------------------------------------
Title: European Commission Approves Once-Weekly Etanercept for Psoriasis
URL: http://www.pslgroup.com/dg/225482.htm
Doctor's Guide
July 8, 2008

NEW YORK -- July 8, 2008 -- The European Commission has approved etanercept (Enbrel) 50 mg once-weekly dosage regimen as an alternative to the currently approved etanercept 25 mg twice-weekly regimen for the treatment of patients with moderate to severe plaque psoriasis.

The approval is based on the outcome of an open-label, placebo-controlled study involving 318 patients with moderate to severe plaque psoriasis.

Patients' quality of life was measured with patient-reported outcome (PRO) impairment, Dermatology Life Quality Index (DLQI) score, and Psoriasis Area and Severity Index (PASI). The primary endpoint was 75% in PASI score.

For 12 weeks, one group of patients received etanercept while the other group was given placebo. After 12 weeks all patients were then prescribed etanercept for an additional 12 weeks. Primary endpoint was achieved at week 12. Patients continued to improve with etanercept treatment at week 24, with a 64%, "clear" or "almost clear" PRO impairment.


SOURCE: Wyeth

---------------------------------------------------------------------------------------------
Copyright © 1999 P\S\L Consulting Group Inc. All rights reserved. Republication or redistribution of P\S\L content is expressly prohibited without the prior written consent of P\S\L. P\S\L shall not be liable for any errors, omissions or delays in this content or any other content on its sites, newsletters or other publications, nor for any decisions or actions taken in reliance on such content.
---------------------------------------------------------------------------------------------
This news story was printed from *Doctor's Guide to the Internet*
located at http://www.docguide.com
---------------------------------------------------------------------------------------

Return to News Story Page

This site is maintained by webmaster@pslgroup.com
Please contact us with any comments, problems or bugs.
All contents Copyright (c) 1998 P\S\L Consulting Group Inc.
All rights reserved.