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Title: Acne: New Treatments for Practical Management
URL: http://www.pslgroup.com/dg/21926.htm
Doctor's Guide
March 23, 1997


SAN FRANCISCO, March 23, 1997 -- There is continued progress in the development of medications to help those who suffer from acne. Several new medications for acne treatment have been made available during the past year, and there are more that will be made available in coming months, according to Alan R. Shalita, M.D., Speaking today at the American Academy of Dermatology's 55th Annual Meeting.

Speaking on "Acne Treatment in 1997." Dr. Shalita, Professor and Chairman of the Department of Dermatology, SUNY HealthSciences Center, Brooklyn, New York, discussed current concepts in the practical management of acne, emphasizing directive treatment to known
pathogenic factors.

Acne treatment has changed over the years as recent studies have produced findings regarding the evolution of acne at its onset, the changing patterns of bacterial resistance to antibiotics and differing opinions on how to use some of the new therapies.

"While none of these is considered a dramatic breakthrough in acne treatment, they are positive therapeutic options that are now available to the dermatologist in managing this very common and frequently, troublesome disease," Dr. Shalita said.

The new medications include:

-- Tretinoin (microencapsulated) - The incorporation of tretinoin in microsponges decreases the potential for irritation in the use of this well- established acne medication.

-- Sodium Sulfacetamide clear lotion - Another 'golden oldie' in acne care, this lotion reduces inflammation and is well tolerated. It is particularly well-suited for adult women, and is preferred over a topical antibiotic.

-- Adapalene - Naphthoic acid is a derivative with retinoid activity. It appears to be less irritating than some forms of tretinoin and is very
effective on acne.

-- Azelaic Acid - This has gotten mixed results in Europe. It provides a broad spectrum of activity in acne cases, but provides a slow onset of action.

-- Tazarotene - This receptor specific retinoid has had activity in both acne and psoriasis treatment.

Dr. Shalita further discussed how these medications can be incorporated into existing treatments as topical, systemic and local office therapies.

The American Academy of Dermatology is the largest medical society representing physicians who specialize in treating skin, hair and nail conditions.

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