To print: Select File and then Print from your browser's menu --------------------------------------------------------------------------------------- Title: AAO-HNSF: Endoscopic CO2 Laser Treatment for Recurrent Glottic Carcinoma Produces Similar Results to Open-Neck Surgery URL: http://www.pslgroup.com/dg/21EED6.htm Doctor's Guide September 27, 2002
By Paula Moyer Special to DG News SAN DIEGO, CA -- September 27, 2002 -- Endoscopic salvage surgery using a CO2 laser is as effective as open-neck surgery in addressing recurrent glottic carcinoma, say researchers. While recurrent glottic carcinoma can be treated either by surgically or endoscopically, an endoscopic approach has the obvious advantage of saving the larynx, said Dr. Roberto Puxeddu, a practicing head and neck surgeon in Cagliari, Italy. He sought to determine whether this approach was as effective as open surgery and presented his and his co-investigators' findings here at the 106th annual meeting of the American Academy of Otolaryngology-Head and Neck Surgery Foundation. In a retrospective review, the team of investigators assessed the outcome of endoscopic salvage surgery with CO2 laser on 16 patients who had recurrent rT1 and rT2 glottic carcinoma. The patients had been treated between February 1995 and December 1999 after their primary tumors had not responded to radiotherapy. The patients were all Caucasian males and were an average of 68.7 years old, with an age range of 50 to 87 years. Prior to radiotherapy, 11 patients had T1 lesions, and five had T2 lesions. None had nodal involvement. After radiotherapy, 12 patients had recurrent rT1, and four had rT2 tumors, again with no nodal involvement. After undergoing endoscopic salvage surgery, the patients were followed for an average of 45 months, with a range of nine to 79 months. Nine patients underwent transmuscular cordectomies and seven underwent extended cordectomies. "The type of cordectomy performed was based on the recurrent lesion's extension," said Dr. Puxeddu. The researchers confirmed that endoscopic salvage surgery was successful in 14 of the 16 patients (87.5 percent). One patient had a subsequent recurrence and survived following an additional endoscopic procedure. Two patients had recurrent disease after endoscopic laser surgery and subsequently died of their disease. A statistical analysis with the Kaplan-Meier method showed local control three years after endoscopic treatment to be 87.1 percent. "Among all 14 survivors, laryngeal preservation was obtained by endoscopic rescue surgery," said Dr. Puxeddu. He said that the results of these cases indicate that, in selected patients who have an early recurrence after primary radiotherapy for T1 and T2 glottic carcinoma, endoscopic salvage surgery is a feasible approach with oncologic results that are equivalent to patients who undergo open-neck rescue therapy. --------------------------------------------------------------------------------------------- Copyright © 1999 P\S\L Consulting Group Inc. All rights reserved. Republication or redistribution of P\S\L content is expressly prohibited without the prior written consent of P\S\L. P\S\L shall not be liable for any errors, omissions or delays in this content or any other content on its sites, newsletters or other publications, nor for any decisions or actions taken in reliance on such content. --------------------------------------------------------------------------------------------- This news story was printed from *Doctor's Guide to the Internet* located at http://www.docguide.com --------------------------------------------------------------------------------------- Return to News Story Page This site is maintained by webmaster@pslgroup.com Please contact us with any comments, problems or bugs. All contents Copyright (c) 1998 P\S\L Consulting Group Inc. All rights reserved.