To print: Select File and then Print from your browser's menu
---------------------------------------------------------------------------------------
Title: Modified Insulin Most Effective for Controlling Post-Meal Blood Sugar Levels
URL: http://www.pslgroup.com/dg/22C9FE.htm
Doctor's Guide
September 17, 2008

ROCKVILLE, Md -- September 17, 2008 -- Premixed insulin analogues are more effective than long-acting analogues for controlling high blood sugar levels after meals in patients with type 2 diabetes, according to report published online in the Annals of Internal Medicine.

The report represents a systematic review of 45 research studies and is intended to provide unbiased, evidence-based information so that clinicians and others can make the best possible treatment decisions.

"While it is clear that premixed insulin analogues offer certain advantages to patients with diabetes, what is good for one patient may not be good for another," said Carolyn M. Clancy, MD, Agency for Healthcare Research and Quality (AHRQ), Rockville, Maryland.

The AHRQ report compared premixed insulin analogues with conventional premixed human insulin, oral diabetes drugs, and 2 other kinds of insulin analogues -- long-acting and rapid-acting analogues.

The findings of the report include the following:
· Long-acting insulin analogues appear to be more effective than premixed insulin analogues in lowering fasting blood sugar levels.
· Premixed insulin analogues are better than long-acting analogues alone in lowering blood sugar levels after a meal with high sugar content.
· Premixed insulin analogues are more effective than long-acting analogues in lowering haemoglobin A1C, which is a highly reliable indicator of chronic high blood sugar.
· Premixed insulin analogues are more effective than noninsulin antidiabetic medications in lowering fasting blood sugar levels.
· Premixed insulin analogues are more likely than long-acting analogues to be associated with hypoglycaemia, and are similar to premixed human insulin preparations in terms of the frequency of hypoglycaemia reported.
· Premixed insulin analogues are associated with a higher frequency of hypoglycaemic events than oral antidiabetic agents are.

The complete report is available at: effectivehealthcare.ahrq.gov

SOURCE: Agency for Healthcare Research and Quality

---------------------------------------------------------------------------------------------
Copyright © 1999 P\S\L Consulting Group Inc. All rights reserved. Republication or redistribution of P\S\L content is expressly prohibited without the prior written consent of P\S\L. P\S\L shall not be liable for any errors, omissions or delays in this content or any other content on its sites, newsletters or other publications, nor for any decisions or actions taken in reliance on such content.
---------------------------------------------------------------------------------------------
This news story was printed from *Doctor's Guide to the Internet*
located at http://www.docguide.com
---------------------------------------------------------------------------------------

Return to News Story Page

This site is maintained by webmaster@pslgroup.com
Please contact us with any comments, problems or bugs.
All contents Copyright (c) 1998 P\S\L Consulting Group Inc.
All rights reserved.