To print: Select File and then Print from your browser's menu --------------------------------------------------------------------------------------- Title: Vardenafil More Effective When Used On-Demand for Erectile Dysfunction URL: http://www.pslgroup.com/dg/229F4A.htm Doctor's Guide August 26, 2008
AMSTERDAM, Netherlands -- August 26, 2008 -- Vardenafil is more efficacious when used on-demand versus nightly in men with erectile dysfunction following bilateral nerve-sparing radical prostatectomy (NSRP), according to a study published in the October issue of European Urology. The multicentre study recruited patients 1 month before they were scheduled to undergo NSRP, between December 2004 and September 2007. A total of 423 patients completed the study. The inclusion of the on-demand dosing regimen enabled comparison of the currently recommended guidelines for the use of phosphodiesterase type 5 (PDE5) inhibitors with a proposed nightly dosing regimen, which was suggested to have potential positive effects on erectile function. The results of the study showed that on-demand use of vardenafil during the treatment period was associated with significantly greater erectile function and sexual intercourse completion rates compared with placebo. The success rates for the vardenafil on-demand group were also higher than for the nightly group. These data indicate that the use of on-demand vardenafil is of greater benefit than nightly treatment in patients following NSRP surgery and, in general, support the on-demand use of PDE5 inhibitors following NSRP surgery over a daily dosing regimen. According to the authors, this prompts reconsideration of the current practice of prescribing nightly PDE5-inhibitor therapy, as on-demand use of vardenafil is equally effective in men with ED following NSRP, a notoriously difficult-to-treat patient population. SOURCE: Elsevier --------------------------------------------------------------------------------------------- Copyright © 1999 P\S\L Consulting Group Inc. All rights reserved. Republication or redistribution of P\S\L content is expressly prohibited without the prior written consent of P\S\L. P\S\L shall not be liable for any errors, omissions or delays in this content or any other content on its sites, newsletters or other publications, nor for any decisions or actions taken in reliance on such content. --------------------------------------------------------------------------------------------- This news story was printed from *Doctor's Guide to the Internet* located at http://www.docguide.com --------------------------------------------------------------------------------------- Return to News Story Page This site is maintained by webmaster@pslgroup.com Please contact us with any comments, problems or bugs. All contents Copyright (c) 1998 P\S\L Consulting Group Inc. All rights reserved.