To print: Select File and then Print from your browser's menu --------------------------------------------------------------------------------------- Title: Oxygen-Saturated Blood Reduces Levels of Damaged Heart Tissue After Heart Attack URL: http://www.pslgroup.com/dg/2162DE.htm Doctor's Guide October 23, 2007
MINNEAPOLIS, MN -- October 23, 2007 -- Late-breaking data presented at TCT 2007, the scientific symposium of the Cardiovascular Research Foundation (CRF), show that an infusion of blood that is "supersaturated" with oxygen (SSO2) can reduce the amount of damaged heart muscle following a heart attack. Despite successful reperfusion -- or restoration of blood flow to the heart with angioplasty following a heart attack -- there is often an area of infarction, or damaged heart muscle caused by the death of cells due to the interruption of oxygen carrying blood. In the AMIHOT II trial, investigators led by Gregg W. Stone, MD, Chairman, Cardiovascular Research Foundation and Professor of Medicine, Columbia University Medical Center sought to determine the efficacy and safety of infusing SSO2 into the previously blocked artery after an angioplasty procedure. "Among high-risk patients with acute anterior myocardial infarction (heart attack) undergoing successful angioplasty within 6 hours of symptom onset, infusion of SSO2 into the myocardial infarct territory results in a significant reduction in the size of the 'infarct zone,' the amount of damaged heart tissue," Stone said. The AMIHOT II trial was conducted with 304 patients randomized at 20 sites in four countries. Data from the study show that the size of the "infarct zone" was 6.5 percent lower in the patients treated with SSO2 than in control patients who did not receive the therapy. In addition, at 30 days after the treatment, the rates of Major Adverse Cardiac Events (MACE) were statistically equivalent between the two groups. SOURCE: Cardiovascular Research Foundation --------------------------------------------------------------------------------------------- Copyright © 1999 P\S\L Consulting Group Inc. All rights reserved. Republication or redistribution of P\S\L content is expressly prohibited without the prior written consent of P\S\L. P\S\L shall not be liable for any errors, omissions or delays in this content or any other content on its sites, newsletters or other publications, nor for any decisions or actions taken in reliance on such content. --------------------------------------------------------------------------------------------- This news story was printed from *Doctor's Guide to the Internet* located at http://www.docguide.com --------------------------------------------------------------------------------------- Return to News Story Page This site is maintained by webmaster@pslgroup.com Please contact us with any comments, problems or bugs. All contents Copyright (c) 1998 P\S\L Consulting Group Inc. All rights reserved.