Auto-generated: February 12 2012 02:10 AM GMT-8

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Source: Circulation  |  Posted 8 years ago

Effect of the first infliximab infusion on sleep and alertness in patients with active rheumatoid arthritis

Infliximab treatment appears to improve disturbances to sleep and alertness in patients with rheumatoid arthritis (RA), and this improvement is unrelated to improvement in joint discomfort, researchers write.

Patients with RA have increased circulating levels of tumour necrosis factor (TNF)-alpha, which may be one of the elements causing the sleep disorders noted in these patients.

To evaluate this issue further, Carlos Zamarron, MD, and colleagues, Hospital Cl

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