Source: DGNews  |  Posted 8 years ago

By Jill Stein

NEW YORK, NY -- May 20, 2003 -- The antihypertensive effect of the angiotensin receptor blocker eprosartan mesylate remains constant throughout a 24-hour dosing period in older patients with isolated systolic hypertension, researchers reported here on May 16th at the 18th Annual Scientific Meeting of the American Society of Hypertension.
Henry A. Punzi, MD, of the Trinity Hypertension Research Institute, Carrollton, Tex, presented results from a randomized, double-blind, placebo controlled study involving patients who did not respond to initial monotherapy. His research team randomized 283 patients to treatment with placebo alone, or in combination with hydrochlorothiazide.

"Isolated systolic pressure occurs in about 20% of persons 80 years of age or older, and effective treatment of isolated systolic hypertension in this population can decrease the risk of stroke and major cardiovascular events," Dr. Punzi pointed out.

The study included a screening visit, a 3