Source: DGNews | Posted 9 years ago
Increased Incidence of Pulmonary Disease Detected with Methotrexate But Not Rheumatoid Arthritis Drugs
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By Rabiya S. Tuma
NEW ORLEANS, LA -- October 29, 2002 -- A meta-analysis of three previously published clinical trials shows that drug-induced pulmonary disease is more common among rheumatoid arthritis patients treated with methotrexate.
The same analysis showed that among those patients treated with leflunomide (Arava) or with etanercept (Enbrel) there were no cases of drug-induced pulmonary disease.
Dr. Grant Cannon, from the University of Utah in Salt Lake City, Utah, and researchers from Immunex Corporation in Seattle, Washington, as well as Aventis in Bridgewater, New Jersey and Stanford University in Stanford, California, United States, presented the findings here October 26 at the annual meeting of the American College of Rheumatology (ACR).
Methotrexate is considered the standard treatment for rheumatoid arthritis. However, Dr. Barbara Finck, with the Immunex Corporation and one of the authors of the new study, said that because of the drug



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