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Title: Oxandrolone Aids Weight Restoration in Chronic Obstructive Pulmonary Disease
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=R
Retrieve&db=PubMed&list_uids=12171812&dopt=Abstract
Chest 2002, 122(2):421-8 "Reversal of COPD-Associated Weight Loss Using the Anabolic Agent Oxandrolone(*)."
08/26/2002 03:37:19 PM
By David Ball


Patients who experience weight loss associated with chronic obstructive pulmonary disease (COPD) can be helped to restore weight with the anabolic agent oxandrolone, say United States researchers. Since oxandrolone is well tolerated in such patients, this effective adjunct should be considered in their comprehensive management, suggest Dr S.S.Yeh and colleagues at the Veterans' Affairs Medical Center, Northport, New York. While negative outcomes are associated with weight loss common in COPD, improved outcomes are associated with weight gain which was found to be primarily lean body mass. In this prospective open-label clinical trial, COPD patients in 25 community based US pulmonary practices were evaluated on the effects of oral oxandrolone, 10 mg [b.i.d. Moderate-to-severe COPD in a primary pulmonary diagnosis was defined by FEV1 of less than 50 percent of predicted and FEV1/FVC ratio less than 0.7, as well as significant involuntary weight loss (weight

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=R
Retrieve&db=PubMed&list_uids=12171812&dopt=Abstract




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