To print: Select File and then Print from your browser's menu

Title: Once Daily Atomoxetine Effective In Attention Deficit Hyperactivity Disorder

URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=R
Retrieve&db=PubMed&list_uids=12411225&dopt=Abstract

Am J Psychiatry 2002; 159: 1896-1901. "Once-Daily Atomoxetine Treatment for Children and Adolescents With Attention Deficit Hyperactivity Disorder: A Randomized, Placebo-Controlled Study."
11/18/2002 12:21:41 PM
By Andrew A. Skolnick

Atomoxetine, administered once daily, is an effective treatment for children and adolescents with attention deficit hyperactivity disorder. David Michelson, MD, medical director of Lilly Research Laboratories, in Indianapolis, Indiana, United States, and colleagues conducted a double-blind clinical trial involving 171 children and adolescents with attention deficit hyperactivity disorder. The children, who ranged in age from 6 to 16 years, were randomly assigned to receive six weeks of treatment with either atomoxetine administered daily or placebo. Outcomes among atomoxetine-treated patients were superior to those in the placebo group as assessed by investigator, parent, and teacher ratings. The treatment effect size (0.71) was similar to those observed in previous atomoxetine studies that used twice-daily dosing, the investigators reported. Parent diary ratings suggested that drug-specific effects were sustained late in the day. Discontinuations due to adverse events were less than three percent for both treatment groups and no serious safety concerns were observed.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=R
Retrieve&db=PubMed&list_uids=12411225&dopt=Abstract

Copyright © 2009 P\S\L Consulting Group Inc. All rights reserved. Republication or redistribution of P\S\L content is expressly prohibited without the prior written consent of P\S\L. P\S\L shall not be liable for any errors, omissions or delays in this content or any other content on its sites, newsletters or other publications, nor for any decisions or actions taken in reliance on such content.