| Summary points: | A 50-year-old with chronic hepatitis C, previously treated with interferon alpha2b and subsequently with lymphoblastoid interferon without any response or cutaneous side effects, presents with thickened patches of red skin covered with silvery-white scales, on the knees, elbows, scalp and trunk 3 months after starting retreatment with pegylated alpha2b interferon plus ribavirin. This case describes the patient's management and outcome, and includes images. The authors discuss similar cases in the literature and comment on the pathogenesis of interferon-induced psoriasis in association with chronic hepatitis C. |