| Summary points: | A previously healthy 35-year-old presents with acute progressive tetraplegia, transcortical motor aphasia, and mild decrease in consciousness during his recovery from influenza type A infection after receiving oseltamivir phosphate and antiviral therapy. This case report details the patient's history, radiological findings, treatment, and outcome, and includes a series of images. The authors discuss the aetiology of corpus callosum splenium lesions due to influenza virus-associated encephalitis/encephalopathy and the role of oseltamivir in this patient's condition. |