| Summary points: | A 43-year-old with history of recurrent depression since the age of 31 and diagnosed with Hashimoto's thyroiditis at age 37 presents with depressed mood, psychomotor retardation, suicidal thoughts, and persecutory ideas, as well as somnolence, fatigue, nausea, and ataxia. This case report details the patient's history, clinical presentation, and response to treatments. The authors discuss potential pathogenic mechanisms linking thyroid autoimmunity with psychopathology. |