| Summary points: | A 38-year-old with untreated AIDS presents with 15-day history of continuous headache, intermittent fever and lightly pruriginous, erythematous papules and nodules that started on the face and spread to the entire tegument in a few days. This case describes the history, presentation, laboratory findings, diagnosis, treatment and outcome, and includes various images. The authors discuss review cases of cutaneous infection with Cryptococcus in the literature, and discuss the differential diagnosis and the effect of the patient's immune state on the choice of drug treatment. |