| Summary points: | A 19-year-old presents with 6-day history of papular purpuric lesions located exclusively on the hands and feet with a sharp demarcation at the wrists and the ankles, oedema, itching, and pain, which were preceded by fever, abdominal pain, anorexia, and asthenia. This case describes the presentation, diagnostic investigations and outcome, and includes images. The authors discuss the pathophysiology of papular purpuric gloves and socks syndrome, signs of systemic involvement, and approaches to diagnosis. |