| Summary points: | This report describes a 60-year-old and a 34-year-old who present with isolated chronic, non-productive cough and who had never taken an angiotensin-converting enzyme inhibitor and whose endoscopic assessments revealed reflux oesophagitis. This case report describes the details of each case, including diagnostic investigations, response to treatment and outcome, and includes various images. The authors discuss the effects of PPIs beyond acid suppression seen in the literature and the role of 24-h oesophageal pH monitoring to determine the precise temporal relationship between cough and acid reflux. |