| Presented by: | Archives of Pathology & Laboratory Medicine / Dena Marrinucci, BS, Kelly Bethel, MD, Madelyn Luttgen, BS, Richard H. Bruce, PhD, Jorge Nieva, MD and Peter Kuhn, PhD |
| Summary points: | In this case study, the authors present the cytomorphology of circulating tumour cells (CTCs) obtained from the blood of a 47-year-old woman with stage IIIB well-differentiated lung adenocarcinoma. Four years after she was diagnosed with her disease, 67 CTCs were identified in a blood sample using an immunofluorescent staining protocol and then subsequently stained with Wright-Giemsa. The cytomorphology of the CTCs was compared with the original tissue biopsy from 4 years prior. The authors suggest that careful cytomorphological evaluation of CTCs can provide insights about the metastatic significance of these cells, which could yield widespread implications for the diagnosis, treatment, and management of cancer. |
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Circulating Tumor Cells From Well-Differentiated Lung Adenocarcinoma Retain Cytomorphologic Features of Primary Tumor Type
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