Concomitant Epstein-Barr Virus-Negative Large B-Cell Lymphoma (Richter Syndrome) and Epstein-Barr Virus - Positive B-Cell Lymphoproliferation after Treatment with Fludarabine and Cyclophosphamide in a Patient With B-Cell Chronic Lymphocytic Leukemia
Presented by:
Archives of Pathology and Laboratory Medicine / Eva Compérat, MD, Alain Delmer, MD, Agnes Le Tourneau, MD, Thierry J. Molina, MD, Jacques Diebold, MD and Josée Audouin, MD
Summary points:
A 54-year-old undergoing treatment for B stage B-cell lymphocytic lymphoma presents with prolonged fever and dysphagia. This case study provides the patient's history, clinical findings and laboratory testing and needle aspiration biopsy results and pathology, treatment and outcome. The authors discuss the relevance of discovering large B cells by needle biopsy in a lymph node from a patient with this condition.