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        news A Woman with Cystic Fibrosis, Severe Hypoxaemia, an Atrial Thrombus and a Patent Foramen Ovale: A Case Report

        Presented by:Journal of Medical Case Reports / Nicholas J Simmonds, Hilary Wyatt, Raj Patel, Margaret E Hodson and Khin M Gyi
        Summary points:A 21-year-old woman with cystic fibrosis (CF) and a totally implantable venous access device (TIVAD) initially presents with a deterioration in her oxygen saturation; 1 month later she presents with transient expressive dysphasia and a right-sided haemiparesis. Lung function, thoracic computed tomography (CT) scan, brain CT, contrast echocardiogram, and cardiac magnetic resonance imaging findings are described; images provided. The authors discuss severe hypoxaemia caused by thrombus formation in the right atrium and stress the need to consider right-to-left shunt in chronic respiratory diseases when hypoxaemia is disproportionate to the degree of impaired lung function.
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