| Summary points: | A 2-year-old on long-term treatment for asthma presents with generalised urticaria, facial angioedema, nausea, and severe dyspnoea after receiving intravenous prednisolone-21-hydrogen succinate. This case report describes the results of the skin prick test, fluorescence enzyme immunoassay analysis, and oral provocation test. The authors review the literature on the pathomechanism of immediate-type hypersensitivity to glucocorticoids, the best approach to clinical diagnosis of this hypersensitivity. |