| Summary points: | A 47-year-old Caucasian male with a 10-year history of Crohn's disease presents with a 5-day history of fever, night sweats, rash over both legs, and headache. The headache was localised at the left temporal area and associated with nausea, lethargy, general malaise, fever, night sweats, and rigors but not photophobia. Medical history, physical examination, laboratory data, computed tomography head scan, lumbar puncture, and treatment are described. The authors discuss their diagnosis of neuro-Sweet syndrome associated with Crohn's disease, which has never been previously reported. |