| Summary points: | A 37-year-old female with autoimmune thyroiditis and primary adrenal insufficiency of autoimmune polyglandular syndrome type 2 (APS-2) presents with newly developed Raynaud's phenomenon. Physical examination, chest x-ray, laboratory tests, and electrocardiography are described. The authors suggest that connective tissue disease may accompany APS-2, and in such cases this should be considered in the differential diagnosis of otherwise unexplained symptoms. |