Scroll Up
Scroll Down
Play Play Play Play
Unregistered User
Click here if this is not your Personal Edition
 
Contact Us | Free E-Mail Updates | Journals | Register a colleague
 
 
Cholesterol/Lipid Disorders
 
   
 
SEARCH   
Doctor's Guide Free CME
Medline
Congress Resource Centre
 

 EXPLORE :
   Most Read News
 All News  All News
 All Webcasts / CME  All Webcasts / CME
 All Cases  All Cases
 Congress Resource Centre  Congress Resource Centre
 All Medical Resources  All Medical Resources
 Medical  My Personal Edition



Warning | Privacy

 

 
 Recent news - Cholesterol/Lipid Disorders
    Certain Biomarkers Have Limitations in Predicting Cardiovascular Events - (DGNews)
    TopAbstracts in Cholesterol/Lipid Disorders 06/25/2009 - (DGNews)
    Treatment With Physiological Levels of Growth Hormone Fails to Show Benefit on Cardiovascular Parameters: Presented at ENDO 09 - (DGDispatch)
    Genetically elevated lipoprotein(a) and increased risk of myocardial infarction - (JAMA)
    TopAbstracts in Cholesterol/Lipid Disorders 06/11/2009 - (DGNews)

    News archive

     Recent webcasts/CME - Cholesterol/Lipid Disorders
      The Evolution of Cardiometabolic Risk Reduction and Mixed Dyslipidemia: Examining the Role of Chronic Obesity Management
      Treatment of Mixed Dyslipidemia
      Artifactual Laboratory Abnormalities in Patients with Paraproteinemia
      Issues in Cardiovascular & Metabolic Risk Management: Highlights from ENDO 08
      Dyslipidemia in Children and Adolescents

      Webcasts/CME archive

       Recent cases - Cholesterol/Lipid Disorders
        Marked Aortic Valve Stenosis Progression After Receiving Long-Term Aggressive Cholesterol-Lowering Therapy Using Low-Density Lipoprotein Apheresis in a Patient With Familial Hypercholesterolemia
        Acute Myocardial Infarction in an 18 Year Old South Indian Girl with Familial Hypercholesterolemia: A Case Report
        Eruptive Xanthomas and Acute Pancreatitis in a Patient with Hypertriglyceridemia
        Abetalipoproteinemia: Two Case Reports and a Literature Review
        Familial Hypercholesterolemia with Coarctation of Aorta

        Cases archive
          




        my personal edition > cholesterol/lipid disorders > news
        divider

          E-Mail this DGReview to a colleague

        DGReview


        Study Supports Blood Lipids as Independent Stroke Risk Factor

        A DGReview of :"Blood Lipids and First-Ever Ischemic Stroke/Transient Ischemic Attack in the Bezafibrate Infarction Prevention (BIP) Registry: High Triglycerides Constitute an Independent Risk Factor"
        Circulation

        12/28/2001
        By Harvey McConnell


        High triglycerides levels in the blood constitute an independent risk factor for ischemic stroke or transient ischemic attacks.

        At the same time, according to Dr. David Tanne and colleagues at the Department of Neurology, Stroke Unit and Neufeld Cardiac Research Institute, Sheba Medical Center, Tel Aviv, Israel, high density lipoprotein (HDL) percentage is an independent protective factor among patients with coronary heart disease (CHD).

        Dr. Tanne and collaborators from the University of Tel Aviv believe their findings support the role of blood lipids, including triglycerides, as important modifiable stroke risk factors.

        Researchers point out, "Despite unclear associations between blood lipids, including fractionated cholesterol and triglycerides, and stroke, recent evidence demonstrates that lipid-modifying agents decrease the risk of stroke in patients with coronary heart disease (CHD)."

        Dr. Tanne and colleagues followed 11,177 patients with documented CHD who were screened for but not included in the Bezafibrate Infarction Prevention Study and had no history of stroke or transient ischemic attack (TIA). Medical histories and blood lipids were assessed at baseline at a central study laboratory.

        During the follow-up of six to eight years, the researchers identified 941 patients as having nonhemorrhagic cerebrovascular disease. Among them, 487 had verified ischemic stroke (as assessed by clinical findings and brain computer tomography) or TIA.

        Patients who experienced an ischemic stroke or TIA had higher mean levels of triglycerides, lower levels of HDL cholesterol, and lower percentages of cholesterol contained in the HDL cholesterol moiety.

        Dr. Tanne and colleagues carried out a logistic regression model assessment. They found the adjusted odds ratios for developing an ischemic stroke/TIA were 1.27 associated with triglycerides levels above 200 mg/dL and 0.87 associated with a five percent decrease in the percentage of HDL.

        Increased risk associated with high triglycerides was found across subgroups of age, sex, patient characteristics, and cholesterol fractions.
        Circulation. 2001;104:2892 "Blood Lipids and First-Ever Ischemic Stroke/Transient Ischemic Attack in the Bezafibrate Infarction Prevention (BIP) Registry: High Triglycerides Constitute an Independent Risk Factor"

        E-Mail this DGReview to a colleague   To print, use this version






        All contents Copyright (c) 1995-2009 Doctor's Guide Publishing Limited. All rights reserved.



        The NTK initiative. Physicians helping physicians identify Need-To-Know science
           Feedback
        Please rate this article: Strongly DISAGREE...Strongly AGREE NTK logo
        Question 1 - Physicians need to become aware of this information as soon as possible. Question 2 - This information is likely to have an impact on the way physicians practice medicine.
        1
        2
        3
        4
        5
        6
        7
        Send