Scroll Up
Scroll Down
Play Play Play Play
Unregistered User
Click here if this is not your Personal Edition
 
Contact Us | Free E-Mail Updates | Journals | Register a colleague
 
 
Thrombosis
 
   
 
SEARCH   
Doctor's Guide Free CME
Medline
Congress Resource Centre
 

 EXPLORE :
   Most Read News
 All News  All News
 All Webcasts / CME  All Webcasts / CME
 All Cases  All Cases
 Congress Resource Centre  Congress Resource Centre
 All Medical Resources  All Medical Resources
 Medical  My Personal Edition



Warning | Privacy

 

 
 Recent news - Thrombosis
    Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty - (N Engl J Med)
    Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty - (N Engl J Med)
    Extended-Use Rivaroxaban Effectively Prevents Venous Thromboembolism After Hip Surgery - (DGNews)
    Drug-Eluting Stents May Decrease Repeat Revascularisation - (DGNews)
    International Panel Agrees on Guidelines for Preventing Thrombosis in Special Patient Groups - (DGNews)

    News archive

     Recent webcasts/CME - Thrombosis
    • Background: Prevention and Management of Venous Thromboembolism in Patients with Cancer: A Case-Based Approach
    • Case Study 1: 62-Year-Old Woman With Stage IV Breast Cancer and Repeated Courses of Chemotherapy
    • Case Study 2: 64-Year-Old Man With Stage III Colorectal Cancer Who Is Scheduled for Surgery
    • Long-Term Effects on Arterial Healing with DES
      Venous Thromboembolism and Acute Coronary Syndrome: Community Pharmacists' Key Position in the Continuum of Care

      Webcasts/CME archive

       Recent cases - Thrombosis
        Sigmoid Sinus Thrombosis Presenting with Posterior Alexia in a Patient with Behcet's Disease And Polycythaemia: A Case Report
        Left Atrial Giant Thrombus Infected by Escherichia Coli. Case Report
        Middle Bile Duct Cancer with Portal Vein Tumor Thrombus
        Pleural Mesothelioma and Venous Thrombosis: The Eosinophilia Link
        Elevated Maternal Lipoprotein (A) and Neonatal Renal Vein Thrombosis: A Case Report

        Cases archive
          




        my personal edition > thrombosis > news
        divider

          E-Mail this DGReview to a colleague

        DGReview


        D-Dimer Assays Not Enough For Diagnosis of Likely Deep Vein Thrombosis

        A DGReview of :"Validity of D-dimer tests in the diagnosis of deep vein thrombosis: a prospective comparative study of three quantitative assays"
        Journal of Internal Medicine

        07/29/2002
        By Anne MacLennan


        A high pretest probability of deep vein thrombosis calls for a differential strategy that distinguishes between cases of low and high clinical probability using either a D-dimer test or ultrasonography.

        This is the conclusion of Danish researchers following an assessment of the diagnostic reliability of a new quantitative D-dimer assay and an established quick test versus ultrasonography in the diagnosis of deep vein thrombosis (DVT).

        A third assay became available during sample collection and is included in the final assessment.

        One hundred and thirteen hospital outpatients with suspected DVT participated in this prospective study by T B Larsen. MD, PhD, and colleagues from the Aalborg Hospital, Aalborg.

        Compression ultrasonography was used as the reference method for a diagnosis of DVT and compared with the different D-dimer assays. Results were expressed as sensitivity, specificity, positive predictive value and negative predictive value (NPV).

        Deep vein thrombosis was established in 49 patients (43 percent) of the 113 patients.

        The two D-dimer assays showed, respectively, sensitivities of 90 percent and 88 percent, specificities of 42 percent and 44 percent and NPVs of 85 percent and 83 percent.

        While the diagnostic performance of the two D-dimer assays is almost identical, these authors suggest neither is suitable as the only screening method for DVT in a situation with a high pretest probability of DVT.
        J Intern Med 2002; 252: 36-40. "Validity of D-dimer tests in the diagnosis of deep vein thrombosis: a prospective comparative study of three quantitative assays"

        E-Mail this DGReview to a colleague   To print, use this version






        All contents Copyright (c) 1995-2008 Doctor's Guide Publishing Limited. All rights reserved.



        The NTK initiative. Physicians helping physicians identify Need-To-Know science
           Feedback
        Please rate this article: Strongly DISAGREE...Strongly AGREE NTK logo
        Question 1 - Physicians need to become aware of this information as soon as possible. Question 2 - This information is likely to have an impact on the way physicians practice medicine.
        1
        2
        3
        4
        5
        6
        7
        Send