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Exclusive Breast-Feeding Effective In Preventing Early Atopic Dermatitis
A DGReview of :"Effect of exclusive breast-feeding and early solid food avoidance on the incidence of atopic dermatitis in high-risk infants at 1 year of age."
Pediatric Allergy and Immunology
10/31/2002
By Elda Hauschildt
Exclusive breast-feeding for at least four months could be effective in preventing early atopic dermatitis (AD) in infants at atopic risk.
German researchers, following 1,121 infants during the first year of life, report an adjusted odds of 0.47 for AD in exclusively breast-fed infants.
This study was part of a dietary clinical trial in a prospective cohort of healthy newborns considered at risk for atopy. Mothers were advised to breast-feed for at least four months and to avoid introducing solid foods in that time period.
A total of 855 infants were breast-fed exclusively. The other 256 babies were partially or exclusively fed formula. All of the children were followed until the end of the first year of life.
Investigators led by Dr. A. Schoetzau of the GSF - National Research Centre for the Environment and Health in Neuherberg compared the incidence of AD and sensitisation to milk and egg in the two groups of infants. They also calculated AD incidence in relation to age at introduction of solid food and the amount of food given.
Family history of AD was found to be the strongest risk factor for AD. Infants with AD had a four times higher risk of being sensitised to milk and an eight times higher risk of sensitisation to egg than infants without AD.
The researchers point out that age at introduction to solid food did not affect AD incidence.
Pediatric Allergy and Immunology, 2002; 13: 234-242.
"Effect of exclusive breast-feeding and early solid food avoidance on the incidence of atopic dermatitis in high-risk infants at 1 year of age."
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