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Delayed Gastric Emptying Associated with Post-Prandial Irritable Bowel Fullness
A DGReview of :"Dyspeptic symptoms and gastric emptying in the irritable bowel syndrome"
American Journal of Gastroenterology
11/21/2002
By Elda Hauschildt
A significant association has been found between delayed gastric emptying of solids and overlapping post-prandial fullness and nausea in patients with irritable bowel syndrome (IBS).
Italian researchers report that IBS patients who do not demonstrate overlapping dyspepsia have normal gastric emptying of solids.
Investigators from S. Orsola-Malpighi University Hospital in Bologna point out that dyspepsia often overlaps with IBS, while delayed gastric emptying has been reported in some IBS patients. They evaluated gastric emptying of solids and its relationship with dyspeptic symptoms in 146 IBS outpatients treated at one referral centre.
Gastric emptying of solids was also assessed in 50 healthy controls.
Overlapping dyspepsia was diagnosed in 96 of the IBS patients (66 percent). Results indicate gastric emptying rates on average were lower in IBS patients than in controls and that gastric emptying was delayed specifically in IBS patients with overlapping dyspepsia.
IBS patients who did not demonstrate dyspeptic complaints had similar gastric emptying rates with to healthy controls.
"Relevant post-prandial fullness (odds ratio [OR], 4.7) and relevant nausea (OR, 3.3) were independently associated with delayed gastric emptying," the researchers note.
They concluded: "A significant association exists in IBS patients between delayed gastric emptying and overlapping relevant post-prandial fullness and nausea."
American Journal of Gastroenterology, 2002; 97: 2738-2743.
"Dyspeptic symptoms and gastric emptying in the irritable bowel syndrome"
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