Scroll Up
Scroll Down
Play Play Play Play
Unregistered User
Click here if this is not your Personal Edition
 
Contact Us | Free E-Mail Updates | Journals | Register a colleague
 
 
Cataract
 
   
 
SEARCH   
Doctor's Guide Free CME
Medline
Congress Resource Centre
 

 EXPLORE :
   Most Read News
 All News  All News
 All Webcasts / CME  All Webcasts / CME
 All Cases  All Cases
 Congress Resource Centre  Congress Resource Centre
 All Medical Resources  All Medical Resources
 Medical  My Personal Edition



Warning | Privacy

 

 
 Recent news - Cataract
    TopAbstracts in Cataract 05/05/2008 - (DGNews)
    Pupil Size Differences Noted With Moxifloxacin and Gatifloxacin Before Eye Surgery: Presented at ARVO - (DGDispatch)
    Hearing Impairment Appears Associated With Vision Problems in Elderly: Presented at ARVO - (DGDispatch)
    TopAbstracts in Cataract 04/07/2008 - (DGNews)
    TopAbstracts in Cataract 03/10/2008 - (DGNews)

    News archive

     Recent webcasts/CME - Cataract
      On The Front Line: Advanced Techniques to Improve Surgical Outcomes Through Tear Film Optimization
      Managing IOP and Ocular Health in Cataract Surgery, Refractive Surgery, and Macular Disease

      Webcasts/CME archive

       Recent cases - Cataract
        Atopic Dermatitis, Cutaneous Steroids and Cataracts in Children: Two Case Reports
        Severe Generalised Hypersensitivity Reaction to Topical Neomycin After Cataract Surgery: A Case Report
        Histopathology in a Dissecting Conjunctival Filtering Bleb
        Medulloepithelioma Masquerading as Chronic Anterior Granulomatous Uveitis
        Perfluorocarbon Liquid Left in Vitreous Cavity after Recovery of Dropped Nuclei by Anterior Segment Surgeons after Cataract Surgery

        Cases archive
          




        my personal edition > cataract > news
        divider

          E-Mail this DGReview to a colleague

        DGReview


        Oxidative Stress Linked to Cataract Formation in Diabetics

        A DGReview of :"Blood and lens lipid peroxidation and antioxidant status in normal individuals, senile and diabetic cataractous patients."
        Current Eye Research

        01/16/2003
        By Mark Greener


        Lens concentrations of glutathione and thiobarbituric acid reactive substances correlate with cataract formation in patients with diabetes.

        Researchers from the Cerrahpasa Medical Faculty at Istanbul University, in Turkey, enrolled 46 patients with cataracts as well as a control group made up of 10 female and 10 male nonsmokers without cataracts, lens opacity or vacuoles.

        Whole blood glutathione levels and erythrocyte superoxide dismutase activities were lower, while plasma levels of thiobarbituric acid reactive substances were higher in patients with cataracts compared to controls.

        Patients with diabetic cataracts showed lower whole blood glutathione levels and erythrocyte superoxide dismutase activity than those with senile cataracts. Patients with diabetic cataracts also showed lower levels of glutathione reductase and glucose-6-phosphate dehydrogenase in red blood cells.

        The researchers also found that patients with senile cataracts had lower glutathione reductase activity and levels of thiobarbituric acid reactive substances compared to those with diabetic cataracts. Levels of glutathione were also higher in the lens of patients with senile compared to diabetic cataracts.

        The authors conclude that the concentrations of glutathione and thiobarbituric acid reactive substances in the lens correlated with cataract formation in patients with diabetes. The authors suggest that their findings underscore the vital role of glutathione as a lens antioxidant.
        Curr Eye Res 2002;25:9-16. "Blood and lens lipid peroxidation and antioxidant status in normal individuals, senile and diabetic cataractous patients."

        E-Mail this DGReview to a colleague   To print, use this version






        All contents Copyright (c) 1995-2008 Doctor's Guide Publishing Limited. All rights reserved.



        The NTK initiative. Physicians helping physicians identify Need-To-Know science
           Feedback
        Please rate this article: Strongly DISAGREE...Strongly AGREE NTK logo
        Question 1 - Physicians need to become aware of this information as soon as possible. Question 2 - This information is likely to have an impact on the way physicians practice medicine.
        1
        2
        3
        4
        5
        6
        7
        Send