Scroll Up
Scroll Down
Play Play Play Play
Unregistered User
Click here if this is not your Personal Edition
 
Contact Us | Free E-Mail Updates | Journals | Register a colleague
 
 
Rheumatology Other
 
   
 
SEARCH   
Doctor's Guide Free CME
Medline
Congress Resource Centre
 

 EXPLORE :
   Most Read News
 All News  All News
 All Webcasts / CME  All Webcasts / CME
 All Cases  All Cases
 Congress Resource Centre  Congress Resource Centre
 All Medical Resources  All Medical Resources
 Medical  My Personal Edition



Warning | Privacy

 

 
 Recent news - Rheumatology Other
    Severe Joint Pain in Multiple Areas Associated With Increased Risk of Falls in Older Adults - (DGNews)
    Rilonacept Approved in the EU for Cryopyrin-Associated Periodic Syndromes - (DGNews)
    Canakinumab Gives Faster, Greater Pain Relief in Refractory Gout Patients: Presented at ACR/ARHP - (DGDispatch)
    Previous Urate-Lowering Therapy Plus Febuxostat Lowers Urate Levels, Number of Flares in Patients With Gout: Presented at ACR/ARHP - (DGDispatch)
    Low-Dose Colchicine Eases Pain Due to Acute Gout Flare: Presented at ACR/ARHP - (DGDispatch)

    News archive

     Recent webcasts/CME - Rheumatology Other
    Biologics and Infections: Common and Rare

    Webcasts/CME archive

     Recent cases - Rheumatology Other
      Pigmented Villonodular Synovitis of the Knee in a Patient on Oral Anticoagulation Therapy: A Case Report
      Rectal Mucosal Prolapse Syndrome as an Unusual Gastrointestinal Manifestation of Sjogren's Syndrome: A Case Report
      HELLP Syndrome, Multiple Liver Infarctions, and Intrauterine Fetal Death in a Patient with Systemic Lupus Erythematosus and Antiphospholipid Syndrome
      Nasal Septal Perforation in a Patient with Takayasu's Arteritis; a Rare Association
      Nummular Keratopathy in a Patient with Hyper-IgD Syndrome

      Cases archive
        




      my personal edition > rheumatology other > news
      divider

        E-Mail this DGReview to a colleague

      DGReview


      Disease Phenotype Similar In Familial, Sporadic Ankylosing Spondylitis

      A DGReview of :"Dutch Patients with Familial and Sporadic Ankylosing Spondylitis Do Not Differ in Disease Phenotype"
      Journal of Rheumatology

      01/28/2003
      By Anne MacLennan


      Patients with familial and sporadic ankylosing spondylitis (AS) do not differ in disease phenotype, suggests a study of patients from the Netherlands.

      Researchers from the Jan van Breemen Institute and the Department of Rheumatology, Vrije Universiteit Medical Centre, both in Amsterdam, sought to assess potential differences in the phenotypic expression of these two forms of AS.

      Participants in the study were 165 patients, 55 with familial and 110 with sporadic AS.

      The familial AS patients were from families where two or more first-degree relatives had the disease. The 110 patients with the sporadic form of the disease, who were matched on age and sex with the familial disease group, had no first-degree family members with the disease.

      Dr Marcel van der Paardt and colleagues found there were no differences between the familial and sporadic forms of the disease with respect to either patients' age at disease onset or their age at diagnosis or in terms of the prevalences of peripheral arthritis and acute anterior uveitis.

      The findings in these two groups of patients thus suggest potential differences in genetic makeup are not reflected in any differences in the phenotypic expression of the two forms of this disease, the investigators conclude.
      J Rheumatol 2002;29:2583-4. "Dutch Patients with Familial and Sporadic Ankylosing Spondylitis Do Not Differ in Disease Phenotype"

      E-Mail this DGReview to a colleague   To print, use this version






      All contents Copyright (c) 1995-2009 Doctor's Guide Publishing Limited. All rights reserved.



      The NTK initiative. Physicians helping physicians identify Need-To-Know science
         Feedback
      Please rate this article: Strongly DISAGREE...Strongly AGREE NTK logo
      Question 1 - Physicians need to become aware of this information as soon as possible. Question 2 - This information is likely to have an impact on the way physicians practice medicine.
      1
      2
      3
      4
      5
      6
      7
      Send