Scroll Up
Scroll Down
Play Play Play Play
Unregistered User
Click here if this is not your Personal Edition
 
Contact Us | Free E-Mail Updates | Journals | Register a colleague
 
 
Thrombosis
 
   
 
SEARCH   
Doctor's Guide Free CME
Medline
Congress Resource Centre
 

 EXPLORE :
   Most Read News
 All News  All News
 All Webcasts / CME  All Webcasts / CME
 All Cases  All Cases
 Congress Resource Centre  Congress Resource Centre
 All Medical Resources  All Medical Resources
 Medical  My Personal Edition



Warning | Privacy

 

 
 Recent news - Thrombosis
    Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty - (N Engl J Med)
    Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty - (N Engl J Med)
    Extended-Use Rivaroxaban Effectively Prevents Venous Thromboembolism After Hip Surgery - (DGNews)
    Drug-Eluting Stents May Decrease Repeat Revascularisation - (DGNews)
    International Panel Agrees on Guidelines for Preventing Thrombosis in Special Patient Groups - (DGNews)

    News archive

     Recent webcasts/CME - Thrombosis
    • Background: Prevention and Management of Venous Thromboembolism in Patients with Cancer: A Case-Based Approach
    • Case Study 1: 62-Year-Old Woman With Stage IV Breast Cancer and Repeated Courses of Chemotherapy
    • Case Study 2: 64-Year-Old Man With Stage III Colorectal Cancer Who Is Scheduled for Surgery
    • Long-Term Effects on Arterial Healing with DES
      Venous Thromboembolism and Acute Coronary Syndrome: Community Pharmacists' Key Position in the Continuum of Care

      Webcasts/CME archive

       Recent cases - Thrombosis
        Sigmoid Sinus Thrombosis Presenting with Posterior Alexia in a Patient with Behcet's Disease And Polycythaemia: A Case Report
        Left Atrial Giant Thrombus Infected by Escherichia Coli. Case Report
        Middle Bile Duct Cancer with Portal Vein Tumor Thrombus
        Pleural Mesothelioma and Venous Thrombosis: The Eosinophilia Link
        Elevated Maternal Lipoprotein (A) and Neonatal Renal Vein Thrombosis: A Case Report

        Cases archive
          




        my personal edition > thrombosis > news
        divider

          E-Mail this DGReview to a colleague

        DGReview


        Prophylaxis And Screening Recommended For Pregnant Women At High Risk Of Venous Thromboembolism

        A DGReview of :"Prediction, prevention, and treatment of venous thromboembolic disease in pregnancy"
        Seminars in Thrombosis and Hemostasis

        05/15/2003
        By Deanna M. Green


        Prophylactic treatment and genetic screening are recommended for women with a higher risk of venous thromboembolism (VTE) during pregnancy and the puerperium, according to a review by Dr. RB Zotz and colleagues from Düsseldorf, Germany.

        Pregnancy is both an acquired and independent risk factor for VTE, and it is the primary cause of morbidity and mortality during pregnancy and the puerperium. Normal physiological changes in blood coagulation and fibrinolysis factors are required to prepare the body for the hemostatic stress of labor, but these changes can lead to VTE in high-risk women.

        It is therefore important for physicians to assess the individual thrombotic risk during pregnancy based on known risk factors. Furthermore, it is necessary to develop a prophylactic protocol based on risk stratification to help prevent VTE during pregnancy.

        Acquired risk factors for VTE during or after pregnancy include maternal age over 35 years, weight over 80 kg, 4 or more pregnancies, cesarean section, oral contraception use, and personal or family history of VTE.

        Women with severe deficiencies in coagulation factors such as antithrombin or protein C have an intermediate to high risk of VTE and should receive heparin prophylaxis during pregnancy.

        Furthermore, women who are carriers of mutations in either Factor V Leiden or prothrombin have about a 1 in 25 chance of thrombosis during pregnancy and the puerperium. Heparin prophylaxis is recommended for these women throughout the gestational period, or at least in the postpartum period.

        Due to the low risk of VTE observed in women without prior thrombosis, routine screening of all pregnant women for congenital thrombophilia is not currently recommended. However, thrombophilia screening is recommended for women with a personal or family history of VTE.
        Semin Thromb Hemost 2003 April;29:2:143-154. "Prediction, prevention, and treatment of venous thromboembolic disease in pregnancy"

        E-Mail this DGReview to a colleague   To print, use this version






        All contents Copyright (c) 1995-2008 Doctor's Guide Publishing Limited. All rights reserved.



        The NTK initiative. Physicians helping physicians identify Need-To-Know science
           Feedback
        Please rate this article: Strongly DISAGREE...Strongly AGREE NTK logo
        Question 1 - Physicians need to become aware of this information as soon as possible. Question 2 - This information is likely to have an impact on the way physicians practice medicine.
        1
        2
        3
        4
        5
        6
        7
        Send