Scroll Up
Scroll Down
Play Play Play Play
Unregistered User
Click here if this is not your Personal Edition
 
Contact Us | Free E-Mail Updates | Journals | Register a colleague
 
 
Bladder Cancer
 
   
 
SEARCH   
Doctor's Guide Free CME
Medline
Congress Resource Centre
 

 EXPLORE :
   Most Read News
 All News  All News
 All Webcasts / CME  All Webcasts / CME
 All Cases  All Cases
 Congress Resource Centre  Congress Resource Centre
 All Medical Resources  All Medical Resources
 Medical  My Personal Edition



Warning | Privacy

 

 
 Recent news - Bladder Cancer
    TopAbstracts in Bladder Cancer 07/01/2009 - (DGNews)
    TopAbstracts in Bladder Cancer 06/03/2009 - (DGNews)
    TopAbstracts in Bladder Cancer 05/06/2009 - (DGNews)
    TopAbstracts in Bladder Cancer 04/08/2009 - (DGNews)
    More Intense Bladder Cancer Treatment Does Not Improve Survival - (DGNews)

    News archive

     Recent webcasts/CME

      Webcasts/CME archive

       Recent cases - Bladder Cancer
        Plasmacytoid Urothelial Carcinoma of the Bladder: A Case Report
        Peritoneal Tuberculosis and Granulomatous Hepatitis Secondary to Treatment of Bladder Cancer with Bacillus Calmette-Guerin
        Primary Osteosarcoma of the Urinary Bladder Following Cyclophosphamide Therapy for Systemic Lupus Erythematosus: A Case Report
        Invasive Carcinoma of Urinary Bladder in a Patient with A Spinal Cord Injury with Non-Functioning Brindley Sacral Anterior Root Stimulator: A Case Report
        Adenocarcinoma of the Bladder Following Nephrogenic Adenoma: A Case Report

        Cases archive
          




        my personal edition > bladder cancer > news
        divider

          E-Mail this DGReview to a colleague

        DGReview


        Primary Chemotherapy Followed By Radical Surgery Of Rhabdomyosarcoma Of The Bladder Or Prostate Appears to Yield Excellent Cure Rates

        A DGReview of :"Rhabdomyosarcoma of the bladder, prostate or vagina: the role of surgery"
        British Journal of Urology (BJU International)

        01/08/2004
        By Jill Taylor


        Primary chemotherapy followed by radical surgery of rhabdomyosarcoma (RMS) of the prostate and/or bladder allows complete tumour resection in the majority of cases and gives excellent cure rates in nearly 80% of patients, say researchers.

        Approximately 20% of RMS, a rare tumour occurring in children, arises from the genitourinary tract. Once treated solely by surgery, RMS treatment options currently include chemotherapy and radiotherapy, resulting in organ preservation and a substantially better prognosis.

        To evaluate the role of radical surgery in patients with RMS of the prostate and/or bladder, Dragana Filipas, MD, of the University of Vienna, Austria, and colleagues retrospectively analysed the outcome of 22 children who were treated with chemotherapy, with or without radical surgery or additional radiotherapy.

        Among the subjects, 20 had received primary polychemotherapy (vincristine, actinomycin D, cyclophosphamide, adriamycin, and later, etoposide and ifosfamide), and 7 had additional radiotherapy. Radical surgery was used in 14 cases, as primary treatment in 2 patients, after chemotherapy in 11 patients, and during disease progression under chemotherapy in 1 patient.

        After a mean follow up of 8.6 years, 5 children with an advanced tumour stage had died and the remaining 17 children had no evidence of disease.

        Complications included bladder contraction after radiotherapy requiring bladder augmentation (2 children), ureteric stenosis after irradiation and continent cutaneous diversion requiring ureteric reimplantation (1 child), ureteric implantation stenosis requiring reimplantaion (1 child), and early pouch perforation by catheter dislocation requiring surgical revision (1 child).

        "Preserving bladder function so that the patients' quality of life is not compromised carries the risk of higher rates of positive margins and tumour relapse," the investigators said. "Radical surgery and current techniques of continent urinary diversion allow for high cure rates and a good quality of life in these children."



        Br J Urol 2004 Jan;93:1:125-9. "Rhabdomyosarcoma of the bladder, prostate or vagina: the role of surgery"

        E-Mail this DGReview to a colleague   To print, use this version






        All contents Copyright (c) 1995-2009 Doctor's Guide Publishing Limited. All rights reserved.



        The NTK initiative. Physicians helping physicians identify Need-To-Know science
           Feedback
        Please rate this article: Strongly DISAGREE...Strongly AGREE NTK logo
        Question 1 - Physicians need to become aware of this information as soon as possible. Question 2 - This information is likely to have an impact on the way physicians practice medicine.
        1
        2
        3
        4
        5
        6
        7
        Send