Scroll Up
Scroll Down
Play Play Play Play
Unregistered User
Click here if this is not your Personal Edition
 
Contact Us | Free E-Mail Updates | Journals | Register a colleague
 
 
Neurologic Other
 
   
 
SEARCH   
Doctor's Guide Free CME
Medline
Congress Resource Centre
 

 EXPLORE :
   Most Read News
 All News  All News
 All Webcasts / CME  All Webcasts / CME
 All Cases  All Cases
 Congress Resource Centre  Congress Resource Centre
 All Medical Resources  All Medical Resources
 Medical  My Personal Edition



Warning | Privacy

 

 
 Recent news - Neurologic Other
    Modafinil Improves Cognitive Performance in Breast Cancer Survivors: Presented at AGS - (DGDispatch)
    Chromosome 6p22 Locus Associated with Clinically Aggressive Neuroblastoma - (N Engl J Med)
    Vasopressin-Receptor Antagonists May Help Treat Wide Range of Conditions - (DGNews)
    Corticosteroids and mortality in children with bacterial meningitis - (JAMA)
    US Guidelines: Botulinum Toxin Effective in Many Neurological Disorders, Not Headache - (DGNews)

    News archive

     Recent webcasts/CME - Neurologic Other
    • Dementia in Hispanic Americans: The Reasons Behind the Risk
    • Modifiable Risk Factors Underlie Higher Dementia Rates in African Americans
    • Battling Chronic Fatigue Syndrome
      Brain Cooling for the Treatment of Perinatal Hypoxic-Ischemic Encephalopathy
      Delirium Update

      Webcasts/CME archive

       Recent cases - Neurologic Other
        Spinal Dural Arteriovenous Fistula: A Treatable Cause of Myelopathy
        Kernicterus by Glucose-6-Phosphate Dehydrogenase Deficiency: A Case Report and Review of the Literature
        Delayed Spinal Extradural Hematoma Following Thoracic Spine Surgery and Resulting in Paraplegia: A Case Report
        Bilateral Superficial Peroneal Nerve Entrapment Secondary to Anorexia Nervosa: A Case Report
        A Ganglion Cyst at the Elbow Causing Superficial Radial Nerve Compression: A Case Report

        Cases archive
          




        my personal edition > neurologic other > news
        divider

          E-Mail this DGDispatch to a colleague

        DGDispatch


        Levodopa Medications Do Not Improve Parkinsonian Speech: Presented at AAN

        By Jill Stein

        SAN FRANCISCO, CA -- April 30, 2004 -- There is no significant improvement in perceptual speech characteristics following administration of levodopa in patients with Parkinson's disease (PD), said researchers presenting study results on April 28th here at the American Academy of Neurology 56th Annual Meeting.

        Speech and voice dysfunction have been reported to affect between 60% and 90% of PD patients.

        Emily K. Plowman, BSc, and co-workers, University of Florida and Malcolm Randall VA Medical Center, Gainesville, Florida, United States, examined the effects of pharmacological treatment of levodopa on 34 perceptual speech dimensions in 16 PD patients.

        The speech characteristics were grouped under 6 physiologic speech subsystems, which included articulation, respiration, resonance, pernation, prosody, and rate.

        The study found no significant differences in perceptual speech characteristics of PD patients off levodopa versus those on levodopa. "This finding is consistent with most studies that have examined the effects of dopaminergic medications on the speech system," Ms. Plowman said.

        Disparate improvements between "speech motor" and "other motor" modalities were revealed, suggesting the existence of non-dopaminergic neural circuitry for the speech system, Ms. Plowman added.

        The researcher also noted that further investigation is warranted using larger samples and across a range of other fine and gross motor modalities.

        "The results highlight the need for a combination of pharmacologic, surgical, and behavioural therapies in an effort to optimise function across all motor modalities," Ms. Plowman concluded.


        [Presentation Title: "Effects of Pharmacological Treatment of Levodopa on Parkinsonian Speech." Abstract #P04.149]



        E-Mail this DGDispatch to a colleague   To print, use this version






        All contents Copyright (c) 1995-2008 Doctor's Guide Publishing Limited. All rights reserved.



        The NTK initiative. Physicians helping physicians identify Need-To-Know science
           Feedback
        Please rate this article: Strongly DISAGREE...Strongly AGREE NTK logo
        Question 1 - Physicians need to become aware of this information as soon as possible. Question 2 - This information is likely to have an impact on the way physicians practice medicine.
        1
        2
        3
        4
        5
        6
        7
        Send