News - Pioglitazone Hydrochloride Approved as Concomitant Therapy With Biguanides for Type 2 Diabetes in Japan

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Pioglitazone Hydrochloride Approved as Concomitant Therapy With Biguanides for Type 2 Diabetes in Japan

NEW YORK -- December 22, 2008 -- An additional indication of concomitant therapy with biguanides has been approved for pioglitazone hydrochloride (Actos) by the Ministry of Health, Labour, and Welfare in Japan, for the treatment of type 2 diabetes.

The approval is based on a randomised, double-blind, comparative study, in which the clinical usefulness of biguanides monotherapy was compared with that of biguanides plus pioglitazone hydrochloride.

Patients receiving biguanides plus pioglitazone hydrochloride showed a statistically significant difference in improving HbA1C without increasing the risk of hypoglycaemia.

Management of type 2 diabetes should also include nutritional counselling, weight reduction as needed, and exercise.

SOURCE: Takeda Pharmaceutical Company Limited

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