Source: Dermatology  |  Posted 9 years ago

Tacalcitol ointment is safe and well-tolerated in the treatment of chronic plaque psoriasis affecting up to 20 percent of the body surface.

Previous studies have shown the benefit of topical vitamin D[_]3[] analogues for treating mild to moderate plaque psoriasis.

Researchers at the University of Antwerp, in Belgium, and at Medical Clinical Affairs, in Hermal, Reinbek, Germany, conducted their study to determine the agent's efficacy in chronic disease.

They enrolled 157 patients in an open-label, multi-centre, clinical phase IV study with a pre/post comparison design. They patients all had chronic plaque psoriasis which covered 7-20 (average 13.3) percent of the body. They were treated with tacalcitol ointment 4